gastroparesis glp 1 🧬 GLP-1s and Gastroparesis: What You Need to Know, GLP-1 receptor agonists (like semaglutide and tirzepatide) have revolutionized weight management and type 2 diabetes care. But as use has Gastroparesis: Symptoms, Causes, Diagnosis, Treatment,

Ozempic, FDA-approved for diabetes), tirzepatide (Zepbound, FDA-approved for weight management

Image representative of 9 independent experiments

Sources: Neelakantan et al., Biochem Pharmacol 2018 | Dimet-Wiley et al., Sci Rep 2024 Security Profile & Chemical Identity Molecular specifications and preclinical safety data 5-Amino-1MQ Chemical Identity A small molecule derived from quinolinium salts, developed at the University of Texas (2017) 5-Amino-1MQ Tolerance & Status Safety data from preclinical studies (DIO mouse model) Published Preclinical Data 3 key studies published in Biochemical Pharmacology and Scientific Reports 35% Reduction of white adipose tissue in 11 days (20 mg/kg, 3 times/day) Physical Effects (11 days) + 40 % Improvement of grip strength in aged mice (22-24 months) Strength & Performance (aged mice) microbiome The combination of 5-Amino-1MQ + caloric restriction establishes a distinct gut microbial profile Protocol & Results Important Notice Search Only Not intended for human consumption

10.1080/21691401.2017.1420073 103 ShanW.ZhuX.LiuM.LiL.ZhongJ.SunW.et al (2015)

Horseradish peroxidase (HRP)-labeled anti-nitrotyrosine (clone 39B6